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Table 10.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Intestine Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 73 82 113 107 116 152 178 175 198 185
Tx with Follow-up Immunosuppression Info 37 55 69 73 88 113 130 120 139 137
Corticosteroids Any in Category 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.2% 86.7% 85.6% 89.8%
Steroids 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.2% 86.7% 85.6% 89.8%
Cyclosporine Any in Category 2.7% 0.0% 0.0% 1.4% 0.0% 0.9% 1.5% 1.7% 1.4% 2.2%
Sandimmmune 2.7% 0.0% 0.0% 1.4% 0.0% 0.0% 0.0% 0.0% 0.7% 0.7%
Neoral 0.0% 0.0% 0.0% 0.0% 0.0% 0.9% 0.8% 1.7% 0.7% 1.5%
Gengraf 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.0% 0.0% 0.0%
Tacrolimus Any in Category 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.5% 98.3% 99.3% 97.8%
Tacrolimus 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.5% 98.3% 97.1% 97.8%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.2% 0.0%
Antimetabolites Any in Category 37.8% 14.5% 15.9% 11.0% 10.2% 12.4% 20.0% 16.7% 18.7% 19.7%
Mycophenolate Mofetil 21.6% 14.5% 2.9% 9.6% 10.2% 8.0% 13.8% 13.3% 12.9% 18.2%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Azathioprine 16.2% 0.0% 13.0% 1.4% 0.0% 4.4% 6.2% 3.3% 5.8% 1.5%
mTOR Inhibitors Any in Category 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 23.8% 19.2% 10.8% 12.4%
Sirolimus 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 23.8% 19.2% 10.8% 12.4%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.