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Table 1.9c

Immunosuppression Use by Organ

Maintenance Regimen at One Year Following Transplantation

2008 Transplants

  Organ
Heart-Lung Heart Intestine Kidney KP Liver Lung PAK PTA
Transplants 27 2,163 185 16,521 837 6,319 1,478 213 223
With Maintenance Use Recorded at 1 Year PostTx 15 1,783 137 14,692 745 4,898 1,145 165 159
Maintenance Regimen CyA 0.0% 0.4% 0.0% 0.1% 0.0% 1.9% 0.1% 0.0% 0.0%
Tac 0.0% 4.0% 27.0% 2.4% 1.3% 28.3% 0.0% 2.4% 11.3%
--- + MMF/MPA 0.0% 0.4% 0.0% 0.2% 0.1% 0.8% 0.0% 1.2% 0.0%
CyA + MMF/MPA 0.0% 4.9% 0.0% 1.2% 0.7% 3.3% 0.2% 1.2% 0.0%
Tac + MMF/MPA 0.0% 24.2% 2.2% 26.3% 17.9% 25.9% 0.7% 22.4% 25.2%
--- + OtherAntimet 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet 0.0% 0.8% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet 0.0% 2.2% 0.0% 0.5% 0.1% 0.5% 0.0% 0.0% 0.0%
--- + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0%
--- + Siro/Evero 0.0% 0.2% 0.7% 0.1% 0.3% 1.6% 0.0% 0.0% 0.0%
CyA + Siro/Evero 0.0% 0.3% 0.0% 0.6% 2.1% 0.3% 0.0% 2.4% 0.0%
Tac + Siro/Evero 0.0% 1.1% 1.5% 0.7% 2.6% 1.2% 0.0% 3.6% 3.1%
--- + MMF/MPA + Siro/Evero 0.0% 0.3% 0.0% 1.0% 0.8% 1.2% 0.0% 1.8% 0.0%
CyA + MMF/MPA + Siro/Evero 0.0% 0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.6% 0.0% 0.6% 1.9% 0.2% 0.0% 0.6% 7.5%
--- + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Steroids 0.0% 0.4% 0.7% 0.3% 0.3% 1.5% 1.3% 0.0% 0.0%
CyA + Steroids 0.0% 0.8% 0.7% 0.4% 0.3% 0.9% 2.4% 0.0% 0.6%
Tac + Steroids 20.0% 4.5% 48.2% 4.8% 5.0% 11.3% 15.5% 2.4% 20.8%
--- + MMF/MPA + Steroids 0.0% 0.7% 0.7% 0.9% 0.9% 0.6% 0.3% 1.8% 0.0%
CyA + MMF/MPA + Steroids 6.7% 11.2% 0.0% 4.1% 1.9% 1.5% 4.3% 1.8% 0.0%
Tac + MMF/MPA + Steroids 46.7% 33.9% 10.9% 48.5% 59.2% 15.4% 48.1% 47.3% 28.9%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.5% 0.0% 0.0%
CyA + OtherAntimet + Steroids 13.3% 0.3% 0.0% 0.1% 0.0% 0.0% 2.3% 0.0% 0.0%
Tac + OtherAntimet + Steroids 6.7% 2.0% 0.7% 1.7% 1.6% 0.2% 17.1% 4.8% 0.0%
--- + Siro/Evero + Steroids 0.0% 0.2% 0.0% 0.4% 0.0% 0.9% 0.2% 0.0% 0.0%
CyA + Siro/Evero + Steroids 0.0% 1.6% 0.0% 0.8% 0.1% 0.2% 0.3% 0.0% 0.0%
Tac + Siro/Evero + Steroids 0.0% 1.5% 6.6% 0.6% 1.6% 0.9% 2.2% 2.4% 1.9%
Other Regimen 6.7% 3.4% 0.0% 3.4% 1.2% 1.3% 4.5% 3.6% 0.6%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with functioning graft and having any immunosuppression info reported 1yr post-transplant.Columns sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF/MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.