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Table 11.6b
Immunosuppression Use for Induction by Discharge Regimen, 2005 to 2009
Recipients with Heart Transplants
Discharge Regimen (w/ or w/o Steroids Use)
All
CyA
Tac
CyA+ MMF
Tac+ MMF
CyA+ Aza
Tac+ Aza
Siro+ MMF
CyA+ Siro
Tac+ Siro
Other
Functioning Graft with Immunosuppression Info at Discharge
95
322
2,526
6,045
154
136
65
7
66
663
10079
% of All Regimens
0.9%
3.2%
25.1%
60.0%
1.5%
1.3%
0.6%
0.1%
0.7%
6.6%
100.0%
Induction Drug
Atgam/NRATG/NRATS
6.3%
6.8%
4.7%
5.2%
11.7%
11.0%
9.2%
57.1%
9.1%
15.2%
6.1%
OKT3
3.2%
0.3%
2.7%
1.7%
30.5%
2.9%
1.5%
0.0%
3.0%
6.3%
2.7%
Thymoglobulin
9.5%
13.4%
14.3%
18.9%
16.2%
37.5%
29.2%
14.3%
57.6%
25.2%
18.4%
Zenapax
6.3%
2.5%
20.9%
10.9%
3.2%
2.9%
6.2%
0.0%
1.5%
32.0%
14.1%
Simulect
12.6%
12.1%
14.1%
15.3%
7.8%
5.1%
16.9%
28.6%
3.0%
25.6%
15.3%
Campath
4.2%
12.7%
0.2%
2.8%
0.6%
0.0%
10.8%
0.0%
0.0%
3.6%
2.5%
No Induction Drugs Recorded
61.1%
53.7%
44.6%
47.9%
30.5%
41.2%
32.3%
28.6%
28.8%
47.7%
46.8%
Source: OPTN/SRTR Data as of October 1, 2010.
Induction drugs include any reported antilymphocyte antibodies and antibodies directed against lymphocyte receptors.
Individual induction drug percentages will not necessarily add up to 100 percent, as patients may be prescribed more than one induction drug.
CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.