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Table 11.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 2000 to 2009

Recipients with Heart Transplants

  Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009
Functioning Graft at Discharge 1,982 2,008 1,977 1,899 1,867 1,956 2,038 2,070 2,037 2,075
With Immunosuppression Info 1,976 1,983 1,966 1,885 1,854 1,934 1,998 2,059 2,028 2,060
Corticosteroids Any in Category 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2% 88.8% 87.4% 88.7%
Steroids 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2% 88.8% 87.4% 88.7%
Cyclosporine Any in Category 80.4% 70.3% 60.1% 58.5% 50.9% 40.1% 38.1% 33.0% 25.6% 18.7%
Cyclosporin 0.1% 0.1% 0.1% 0.1% 0.2% 0.6% 1.4% 1.1% 1.5% 1.2%
Sandimmmune 8.1% 4.3% 2.8% 3.4% 2.9% 2.1% 1.5% 1.2% 0.6% 1.0%
Neoral 70.6% 57.7% 44.5% 40.6% 33.3% 25.5% 26.8% 23.5% 17.7% 11.7%
Gengraf 1.6% 8.1% 12.6% 14.3% 14.2% 11.2% 8.3% 7.0% 5.5% 4.2%
Eon 0.0% 0.2% 0.2% 0.1% 0.4% 0.7% 0.2% 0.2% 0.3% 0.6%
Tacrolimus Any in Category 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6% 65.4% 73.1% 79.1%
Tacrolimus 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6% 65.0% 72.4% 78.6%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.6% 0.5%
Antimetabolites Any in Category 88.2% 91.0% 84.4% 89.2% 94.9% 94.3% 91.4% 91.9% 92.8% 92.0%
Mycophenolate Mofetil 68.3% 75.8% 71.7% 79.6% 85.3% 84.7% 83.4% 85.6% 87.3% 85.2%
Mycophenolate Sodium 0.0% 0.0% 0.4% 0.2% 0.1% 1.4% 3.4% 3.4% 2.7% 3.7%
Azathioprine 19.5% 14.9% 12.2% 9.3% 9.5% 8.1% 4.7% 2.9% 2.8% 3.1%
Leflunomide 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.4% 0.3% 0.2% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 2.9% 4.3% 10.0% 8.4% 5.3% 4.1% 6.2% 4.5% 3.4% 1.9%
Sirolimus 2.6% 4.3% 10.0% 8.4% 5.2% 3.8% 3.7% 1.2% 1.0% 1.4%
Everolimus 0.4% 0.0% 0.1% 0.0% 0.2% 0.4% 2.6% 3.3% 2.4% 0.5%


Source: OPTN/SRTR Data as of October 1, 2010.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may

be prescribed more than one drug within the same category.