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Table 12.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Lung Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 922 977 1,083 1,054 1,099 1,185 1,407 1,406 1,471 1,478
Tx with Follow-up Immunosuppression Info 665 735 804 829 884 979 1,121 1,144 1,155 1,150
Corticosteroids Any in Category 99.1% 98.6% 99.5% 97.0% 97.9% 99.3% 99.2% 97.8% 98.9% 99.3%
Steroids 99.1% 98.6% 99.5% 97.0% 97.9% 99.3% 99.2% 97.8% 98.9% 99.3%
Cyclosporine Any in Category 63.8% 54.6% 45.9% 35.2% 30.9% 24.4% 23.0% 17.0% 14.3% 12.6%
Cyclosporin 0.0% 0.3% 0.5% 0.1% 0.0% 0.1% 0.5% 1.4% 0.8% 1.1%
Sandimmmune 4.7% 4.2% 5.0% 2.5% 2.7% 1.2% 1.8% 1.6% 1.1% 1.4%
Neoral 58.6% 48.2% 34.0% 25.9% 20.8% 17.6% 14.9% 9.3% 9.7% 7.9%
Gengraf 0.3% 1.9% 6.3% 6.5% 7.1% 5.5% 5.5% 4.6% 2.2% 1.9%
Eon 0.2% 0.0% 0.1% 0.1% 0.2% 0.0% 0.3% 0.1% 0.5% 0.3%
Tacrolimus Any in Category 46.6% 55.6% 69.2% 75.8% 76.1% 83.7% 85.7% 89.3% 92.3% 91.2%
Tacrolimus 46.6% 55.6% 69.2% 75.8% 76.1% 83.7% 85.7% 88.6% 91.7% 90.4%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.7% 0.6% 0.8%
Antimetabolites Any in Category 91.4% 94.3% 90.8% 88.8% 87.7% 88.7% 91.8% 92.5% 90.5% 88.4%
Mycophenolate Mofetil 33.8% 40.8% 42.3% 45.1% 46.5% 49.2% 52.1% 52.0% 52.3% 52.8%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 3.4% 3.1% 7.2% 9.1%
Azathioprine 57.6% 53.3% 48.1% 43.7% 41.2% 39.2% 36.1% 37.4% 30.9% 26.3%
Leflunomide 0.0% 0.0% 0.2% 0.0% 0.0% 0.0% 0.2% 0.0% 0.1% 0.3%
Cytoxan 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 6.2% 6.3% 11.1% 14.4% 10.3% 8.6% 7.9% 6.7% 6.8% 6.0%
Sirolimus 5.9% 6.3% 11.1% 14.4% 10.3% 8.6% 7.9% 6.7% 6.8% 6.0%
Everolimus 0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.



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