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Table 12.6h
Persistency of Discharge Regimen by Follow-up Period, 2004 to 2008
Recipients with Lung Transplants
Year of Transplant
2004
2005
2006
2007
2008
Discharge Regimen (w/ or w/o Steroid Use)
CyA+Aza
At Discharge (N)
179
155
95
90
51
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
55.9%
77.4%
74.7%
84.4%
51.5%
2 Years PostTx (%)
26.3%
31.6%
34.2%
24.0%
12.7%
3 Years PostTx (%)
16.8%
24.9%
17.7%
16.0%
-
CyA+MMF
At Discharge (N)
111
102
84
31
40
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
58.6%
71.6%
56.0%
41.9%
60.3%
2 Years PostTx (%)
34.5%
47.1%
35.7%
19.4%
37.5%
3 Years PostTx (%)
26.7%
31.9%
29.4%
0.0%
-
Siro+MMF
At Discharge (N)
4
2
1
1
1
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
25.0%
50.0%
0.0%
0.0%
0.0%
2 Years PostTx (%)
25.0%
50.0%
0.0%
0.0%
0.0%
3 Years PostTx (%)
25.0%
50.0%
0.0%
0.0%
0.0%
Tac+Aza
At Discharge (N)
274
314
370
322
315
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
67.0%
64.5%
75.6%
67.6%
62.0%
2 Years PostTx (%)
46.9%
46.8%
48.6%
48.8%
41.2%
3 Years PostTx (%)
34.5%
36.2%
38.6%
35.5%
-
Tac+MMF
At Discharge (N)
394
569
611
773
807
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
84.1%
78.3%
82.8%
75.6%
71.5%
2 Years PostTx (%)
69.3%
64.0%
68.5%
58.8%
55.0%
3 Years PostTx (%)
58.8%
53.8%
56.9%
46.5%
-
Tac+Siro
At Discharge (N)
4
3
11
2
2
At Discharge (%)
100.0%
100.0%
100.0%
100.0%
100.0%
1 Year PostTx (%)
75.0%
66.7%
90.9%
100.0%
50.0%
2 Years PostTx (%)
50.0%
33.3%
54.5%
100.0%
-
3 Years PostTx (%)
50.0%
0.0%
45.5%
100.0%
-
Source: OPTN/SRTR Data as of October 1, 2010.
Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen
(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.&
Rates are calculated for the most common discharge regimens.
CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.
See Technical Notes for further details.