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Table 13.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1999 to 2008

Recipients with Heart-Lung Transplants

  Transplant Year
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 51 48 27 33 29 40 35 31 31 27
Functioning Graft at 1 Year PostTx 28 29 21 21 13 31 26 20 27 17
With Maintenance Use Recorded at 1 Year PostTx 26 28 21 21 13 30 26 20 26 15
Tac 0.0% 3.6% 0.0% 0.0% 7.7% 0.0% 3.8% 0.0% 0.0% 0.0%
CyA + MMF/MPA 0.0% 0.0% 4.8% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA 0.0% 0.0% 9.5% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.8% 0.0% 0.0% 0.0%
CyA + Steroids 7.7% 7.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Steroids 0.0% 7.1% 14.3% 9.5% 7.7% 10.0% 7.7% 15.0% 42.3% 20.0%
--- + MMF/MPA + Steroids 0.0% 3.6% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + MMF/MPA + Steroids 19.2% 3.6% 14.3% 14.3% 7.7% 13.3% 7.7% 0.0% 7.7% 6.7%
Tac + MMF/MPA + Steroids 23.1% 32.1% 23.8% 28.6% 38.5% 36.7% 50.0% 60.0% 38.5% 46.7%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 4.8% 0.0% 3.3% 0.0% 5.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 23.1% 17.9% 4.8% 14.3% 15.4% 10.0% 7.7% 5.0% 0.0% 13.3%
Tac + OtherAntimet + Steroids 23.1% 14.3% 28.6% 19.0% 23.1% 20.0% 15.4% 10.0% 7.7% 6.7%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 4.8% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + Siro/Evero + Steroids 0.0% 3.6% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Siro/Evero + Steroids 3.8% 3.6% 0.0% 0.0% 0.0% 6.7% 3.8% 0.0% 0.0% 0.0%
Other Regimen 0.0% 3.6% 0.0% 4.8% 0.0% 0.0% 0.0% 5.0% 3.8% 6.7%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.