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Table 13.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Heart-Lung Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 51 48 27 33 29 40 35 31 31 27
Tx with Follow-up Immunosuppression Info 28 29 21 21 13 30 26 20 26 15
Corticosteroids Any in Category 96.4% 100.0% 95.2% 100.0% 92.3% 100.0% 100.0% 100.0% 100.0% 100.0%
Steroids 96.4% 100.0% 95.2% 100.0% 92.3% 100.0% 100.0% 100.0% 100.0% 100.0%
Cyclosporine Any in Category 53.6% 58.6% 47.6% 52.4% 38.5% 36.7% 50.0% 15.0% 7.7% 20.0%
Cyclosporin 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 6.7%
Sandimmmune 0.0% 6.9% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Neoral 53.6% 44.8% 42.9% 47.6% 23.1% 26.7% 30.8% 5.0% 3.8% 6.7%
Gengraf 0.0% 6.9% 4.8% 4.8% 15.4% 10.0% 19.2% 10.0% 3.8% 6.7%
Eon 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tacrolimus Any in Category 50.0% 58.6% 76.2% 66.7% 76.9% 73.3% 84.6% 90.0% 96.2% 80.0%
Tacrolimus 50.0% 58.6% 76.2% 66.7% 76.9% 73.3% 84.6% 90.0% 96.2% 80.0%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Antimetabolites Any in Category 89.3% 93.1% 95.2% 95.2% 84.6% 90.0% 100.0% 100.0% 76.9% 93.3%
Mycophenolate Mofetil 42.9% 48.3% 47.6% 38.1% 38.5% 43.3% 53.8% 60.0% 65.4% 66.7%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.8% 0.0%
Azathioprine 46.4% 44.8% 47.6% 57.1% 46.2% 46.7% 46.2% 40.0% 7.7% 26.7%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 3.6% 10.3% 0.0% 9.5% 0.0% 6.7% 7.7% 0.0% 3.8% 6.7%
Sirolimus 3.6% 10.3% 0.0% 9.5% 0.0% 6.7% 7.7% 0.0% 3.8% 6.7%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.