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Table 14.10
De Novo Posttransplant Solid Malignancy, 2000 to 2009
Heart Recipients
Malignancies by Type
Year of Transplant
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
Total # of Post-Tx Malignancies
583
504
413
331
276
293
222
141
82
28
Squamous/Basal Cell Carcinoma
318
312
240
200
147
177
144
77
56
16
Melanoma
19
19
10
16
11
11
10
5
2
1
Kaposi Sarcoma
-
1
-
-
-
-
3
3
2
-
Central Nervous System
5
-
-
-
-
1
3
-
-
-
Genito-Urinary (1)
82
58
50
47
49
40
32
17
5
2
Gastro-Intestinal (2)
34
19
23
19
9
8
10
9
3
2
Primary Hepatic Tumor
3
3
-
1
-
1
-
1
-
-
Metastatic Hepatic Tumor
5
3
7
6
3
1
-
-
1
-
Larynx/Bronchi/Lung
55
51
45
23
31
27
8
12
4
3
Breast/Thyroid
10
17
7
9
7
9
6
9
1
-
Leukemia
2
-
6
-
5
2
-
-
-
1
Sarcoma (3)
4
1
4
-
1
-
-
-
-
-
Other
41
18
21
8
12
15
4
7
8
3
Unknown
5
2
-
2
1
1
2
1
-
-
Squamous/Basal Cell Carcinoma
54.5%
61.9%
58.1%
60.4%
53.3%
60.4%
64.9%
54.6%
68.3%
57.1%
Melanoma
3.3%
3.8%
2.4%
4.8%
4.0%
3.8%
4.5%
3.5%
2.4%
3.6%
Kaposi Sarcoma
-
0.2%
-
-
-
-
1.4%
2.1%
2.4%
-
Central Nervous System
0.9%
-
-
-
-
0.3%
1.4%
-
-
-
Genito-Urinary (1)
14.1%
11.5%
12.1%
14.2%
17.8%
13.7%
14.4%
12.1%
6.1%
7.1%
Gastro-Intestinal (2)
5.8%
3.8%
5.6%
5.7%
3.3%
2.7%
4.5%
6.4%
3.7%
7.1%
Primary Hepatic Tumor
0.5%
0.6%
-
0.3%
-
0.3%
-
0.7%
-
-
Metastatic Hepatic Tumor
0.9%
0.6%
1.7%
1.8%
1.1%
0.3%
-
-
1.2%
-
Larynx/Bronchi/Lung
9.4%
10.1%
10.9%
6.9%
11.2%
9.2%
3.6%
8.5%
4.9%
10.7%
Breast/Thyroid
1.7%
3.4%
1.7%
2.7%
2.5%
3.1%
2.7%
6.4%
1.2%
-
Leukemia
0.3%
-
1.5%
-
1.8%
0.7%
-
-
-
3.6%
Sarcoma (3)
0.7%
0.2%
1.0%
-
0.4%
-
-
-
-
-
Other
7.0%
3.6%
5.1%
2.4%
4.3%
5.1%
1.8%
5.0%
9.8%
10.7%
Unknown
0.9%
0.4%
-
0.6%
0.4%
0.3%
0.9%
0.7%
-
-
Total # of Patients
330
294
245
203
181
180
150
110
66
24
Source: OPTN/SRTR Data as of October 1, 2010.
(-) = None in category.
(1) Genito-Urinary: kidney, bladder, uterine cervix, uterine body, ovarian, vulva, testicular, prostate.
(2) Gastro-Intestinal: tongue, throat, esophagus, stomach, small intestine, colo-rectal, liver and biliary tract, pancreas.
(3) Sarcoma: fibrosarcoma, osteosarcoma, etc.
Recipient malignancy statistics are based on voluntary reporting to the OPTN.