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Table 15.4a

Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 5,197 5,684 5,744 5,463 5,448 5,354 5,295 5,286 5,332
Steroids Withdrawn 244 263 438 431 500 691 561 627 624
Rate 4.7% 4.6% 7.6% 7.9% 9.2% 12.9% 10.6% 11.9% 11.7%
CyA Patients 180 83 80 87 91 32 24 23 11
Steroids Withdrawn 20 2 7 6 2 1 1 1 1
Rate 11.1% 2.4% 8.8% 6.9% 2.2% 3.1% 4.2% 4.3% 9.1%
Tac Patients 159 232 213 129 168 195 116 146 136
Steroids Withdrawn 14 30 31 21 44 43 9 12 18
Rate 8.8% 12.9% 14.6% 16.3% 26.2% 22.1% 7.8% 8.2% 13.2%
CyA+MMF Patients 2,053 1,714 1,536 1,238 1,008 728 538 414 305
Steroids Withdrawn 51 36 54 72 65 45 25 38 32
Rate 2.5% 2.1% 3.5% 5.8% 6.4% 6.2% 4.6% 9.2% 10.5%
Tac+MMF Patients 1,667 2,334 2,863 3,025 3,373 3,733 3,902 4,257 4,432
Steroids Withdrawn 91 112 225 223 312 478 470 517 494
Rate 5.5% 4.8% 7.9% 7.4% 9.2% 12.8% 12.0% 12.1% 11.1%
CyA+Aza Patients 205 106 51 27 14 7 7 9 6
Steroids Withdrawn 4 2 2 1 0 0 0 0 2
Rate 2.0% 1.9% 3.9% 3.7% 0.0% 0.0% 0.0% 0.0% 33.3%
Tac+Aza Patients 49 78 56 42 23 12 16 10 19
Steroids Withdrawn 11 7 11 3 1 1 1 0 1
Rate 22.4% 9.0% 19.6% 7.1% 4.3% 8.3% 6.3% 0.0% 5.3%
CyA+Siro Patients 270 251 157 150 108 83 73 56 77
Steroids Withdrawn 7 5 11 8 4 12 0 4 3
Rate 2.6% 2.0% 7.0% 5.3% 3.7% 14.5% 0.0% 7.1% 3.9%
Tac+Siro Patients 236 350 233 285 195 122 179 63 43
Steroids Withdrawn 15 32 32 23 5 15 13 2 2
Rate 6.4% 9.1% 13.7% 8.1% 2.6% 12.3% 7.3% 3.2% 4.7%
Siro+MMF Patients 68 188 213 154 133 111 86 52 40
Steroids Withdrawn 2 7 9 18 14 8 6 7 5
Rate 2.9% 3.7% 4.2% 11.7% 10.5% 7.2% 7.0% 13.5% 12.5%
Other Regimen Patients 310 348 342 326 335 331 354 256 263
Steroids Withdrawn 29 30 56 56 53 88 36 46 66
Rate 9.4% 8.6% 16.4% 17.2% 15.8% 26.6% 10.2% 18.0% 25.1%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use one year after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.