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Table 15.4b

Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 3,895 4,393 4,377 4,113 3,738 3,457 3,185 2,822 2,824
Steroids Withdrawn 182 241 463 466 455 487 381 382 308
Rate 4.7% 5.5% 10.6% 11.3% 12.2% 14.1% 12.0% 13.5% 10.9%
CyA Patients 145 104 70 84 86 19 16 16 3
Steroids Withdrawn 6 4 3 3 2 1 1 1 0
Rate 4.1% 3.8% 4.3% 3.6% 2.3% 5.3% 6.3% 6.3% 0.0%
Tac Patients 141 161 134 117 123 78 74 79 71
Steroids Withdrawn 14 20 17 17 24 17 3 14 8
Rate 9.9% 12.4% 12.7% 14.5% 19.5% 21.8% 4.1% 17.7% 11.3%
CyA+MMF Patients 1,614 1,457 1,167 902 744 542 356 276 241
Steroids Withdrawn 46 36 70 35 43 36 24 29 14
Rate 2.9% 2.5% 6.0% 3.9% 5.8% 6.6% 6.7% 10.5% 5.8%
Tac+MMF Patients 1,164 1,740 2,159 2,229 2,196 2,342 2,238 2,117 2,274
Steroids Withdrawn 59 105 213 272 273 318 316 302 243
Rate 5.1% 6.0% 9.9% 12.2% 12.4% 13.6% 14.1% 14.3% 10.7%
CyA+Aza Patients 163 132 49 17 11 4 5 1 1
Steroids Withdrawn 4 0 3 0 1 0 0 0 0
Rate 2.5% 0.0% 6.1% 0.0% 9.1% 0.0% 0.0% 0.0% 0.0%
Tac+Aza Patients 50 67 74 62 35 6 8 12 10
Steroids Withdrawn 9 10 13 3 3 1 1 0 0
Rate 18.0% 14.9% 17.6% 4.8% 8.6% 16.7% 12.5% 0.0% 0.0%
CyA+Siro Patients 231 156 108 101 43 42 21 19 24
Steroids Withdrawn 13 6 37 31 1 5 1 1 1
Rate 5.6% 3.8% 34.3% 30.7% 2.3% 11.9% 4.8% 5.3% 4.2%
Tac+Siro Patients 172 300 277 237 164 120 184 36 7
Steroids Withdrawn 11 40 54 41 28 18 16 3 1
Rate 6.4% 13.3% 19.5% 17.3% 17.1% 15.0% 8.7% 8.3% 14.3%
Siro+MMF Patients 30 89 124 112 75 101 65 41 46
Steroids Withdrawn 1 0 16 10 5 21 5 3 8
Rate 3.3% 0.0% 12.9% 8.9% 6.7% 20.8% 7.7% 7.3% 17.4%
Other Regimen Patients 185 187 215 252 261 203 218 225 147
Steroids Withdrawn 19 20 37 54 75 70 14 29 33
Rate 10.3% 10.7% 17.2% 21.4% 28.7% 34.5% 6.4% 12.9% 22.4%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use one year after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.