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Table 15.4b
Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008
Recipients of Living Donor Kidneys
Discharge Regimen
Year of Transplant
2000
2001
2002
2003
2004
2005
2006
2007
2008
Total
Patients
3,895
4,393
4,377
4,113
3,738
3,457
3,185
2,822
2,824
Steroids Withdrawn
182
241
463
466
455
487
381
382
308
Rate
4.7%
5.5%
10.6%
11.3%
12.2%
14.1%
12.0%
13.5%
10.9%
CyA
Patients
145
104
70
84
86
19
16
16
3
Steroids Withdrawn
6
4
3
3
2
1
1
1
0
Rate
4.1%
3.8%
4.3%
3.6%
2.3%
5.3%
6.3%
6.3%
0.0%
Tac
Patients
141
161
134
117
123
78
74
79
71
Steroids Withdrawn
14
20
17
17
24
17
3
14
8
Rate
9.9%
12.4%
12.7%
14.5%
19.5%
21.8%
4.1%
17.7%
11.3%
CyA+MMF
Patients
1,614
1,457
1,167
902
744
542
356
276
241
Steroids Withdrawn
46
36
70
35
43
36
24
29
14
Rate
2.9%
2.5%
6.0%
3.9%
5.8%
6.6%
6.7%
10.5%
5.8%
Tac+MMF
Patients
1,164
1,740
2,159
2,229
2,196
2,342
2,238
2,117
2,274
Steroids Withdrawn
59
105
213
272
273
318
316
302
243
Rate
5.1%
6.0%
9.9%
12.2%
12.4%
13.6%
14.1%
14.3%
10.7%
CyA+Aza
Patients
163
132
49
17
11
4
5
1
1
Steroids Withdrawn
4
0
3
0
1
0
0
0
0
Rate
2.5%
0.0%
6.1%
0.0%
9.1%
0.0%
0.0%
0.0%
0.0%
Tac+Aza
Patients
50
67
74
62
35
6
8
12
10
Steroids Withdrawn
9
10
13
3
3
1
1
0
0
Rate
18.0%
14.9%
17.6%
4.8%
8.6%
16.7%
12.5%
0.0%
0.0%
CyA+Siro
Patients
231
156
108
101
43
42
21
19
24
Steroids Withdrawn
13
6
37
31
1
5
1
1
1
Rate
5.6%
3.8%
34.3%
30.7%
2.3%
11.9%
4.8%
5.3%
4.2%
Tac+Siro
Patients
172
300
277
237
164
120
184
36
7
Steroids Withdrawn
11
40
54
41
28
18
16
3
1
Rate
6.4%
13.3%
19.5%
17.3%
17.1%
15.0%
8.7%
8.3%
14.3%
Siro+MMF
Patients
30
89
124
112
75
101
65
41
46
Steroids Withdrawn
1
0
16
10
5
21
5
3
8
Rate
3.3%
0.0%
12.9%
8.9%
6.7%
20.8%
7.7%
7.3%
17.4%
Other Regimen
Patients
185
187
215
252
261
203
218
225
147
Steroids Withdrawn
19
20
37
54
75
70
14
29
33
Rate
10.3%
10.7%
17.2%
21.4%
28.7%
34.5%
6.4%
12.9%
22.4%
Source: OPTN/SRTR Data as of October 1, 2010.
Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning
graft and maintenance drug use one year after transplantation.
CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;
Siro: Sirolimus.