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Table 15.5a

Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 2,893 2,993 3,235 3,198 3,435 3,375 3,572 3,384 3,414
Steroids Withdrawn 1,146 1,370 1,670 1,630 1,750 1,841 1,934 1,994 2,087
Rate 39.6% 45.8% 51.6% 51.0% 50.9% 54.5% 54.1% 58.9% 61.1%
CyA Patients 193 92 75 50 42 42 25 26 19
Steroids Withdrawn 45 41 42 17 19 23 17 15 11
Rate 23.3% 44.6% 56.0% 34.0% 45.2% 54.8% 68.0% 57.7% 57.9%
Tac Patients 994 1,072 1,269 1,138 1,158 1,040 950 847 694
Steroids Withdrawn 467 521 704 596 578 555 500 491 417
Rate 47.0% 48.6% 55.5% 52.4% 49.9% 53.4% 52.6% 58.0% 60.1%
CyA+MMF Patients 224 188 150 139 139 142 142 138 155
Steroids Withdrawn 52 61 63 57 68 81 78 79 99
Rate 23.2% 32.4% 42.0% 41.0% 48.9% 57.0% 54.9% 57.2% 63.9%
Tac+MMF Patients 956 1,171 1,331 1,544 1,760 1,912 2,239 2,231 2,350
Steroids Withdrawn 391 545 683 823 928 1,064 1,215 1,339 1,477
Rate 40.9% 46.5% 51.3% 53.3% 52.7% 55.6% 54.3% 60.0% 62.9%
CyA+Aza Patients 97 47 44 1 24 12 5 3 4
Steroids Withdrawn 15 4 12 0 7 4 1 2 1
Rate 15.5% 8.5% 27.3% 0.0% 29.2% 33.3% 20.0% 66.7% 25.0%
Tac+Aza Patients 64 59 77 80 26 3 3 8 6
Steroids Withdrawn 11 15 17 15 14 0 2 2 3
Rate 17.2% 25.4% 22.1% 18.8% 53.8% 0.0% 66.7% 25.0% 50.0%
CyA+Siro Patients 13 8 21 18 19 17 3 3 11
Steroids Withdrawn 7 3 14 9 14 13 2 1 2
Rate 53.8% 37.5% 66.7% 50.0% 73.7% 76.5% 66.7% 33.3% 18.2%
Tac+Siro Patients 135 134 85 41 52 37 44 18 12
Steroids Withdrawn 63 67 57 23 23 19 30 12 7
Rate 46.7% 50.0% 67.1% 56.1% 44.2% 51.4% 68.2% 66.7% 58.3%
Siro+MMF Patients 27 39 34 32 31 30 23 13 18
Steroids Withdrawn 11 16 20 16 14 17 14 8 8
Rate 40.7% 41.0% 58.8% 50.0% 45.2% 56.7% 60.9% 61.5% 44.4%
Other Regimen Patients 190 183 149 155 184 140 138 97 145
Steroids Withdrawn 84 97 58 74 85 65 75 45 62
Rate 44.2% 53.0% 38.9% 47.7% 46.2% 46.4% 54.3% 46.4% 42.8%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use one year after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.