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Table 15.5a

Steroid Withdrawal Rate at Two Years Following Transplantation, 2000 to 2007

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007
Total Patients 2,812 2,769 2,973 2,952 3,164 2,649 2,550 2,619
Steroids Withdrawn 1,724 1,801 1,979 2,001 2,135 1,913 1,873 1,908
Rate 61.3% 65.0% 66.6% 67.8% 67.5% 72.2% 73.5% 72.9%
CyA Patients 181 88 69 47 37 34 14 20
Steroids Withdrawn 101 57 53 28 27 25 8 15
Rate 55.8% 64.8% 76.8% 59.6% 73.0% 73.5% 57.1% 75.0%
Tac Patients 965 987 1,183 1,063 1,068 859 687 662
Steroids Withdrawn 654 675 801 749 689 604 481 470
Rate 67.8% 68.4% 67.7% 70.5% 64.5% 70.3% 70.0% 71.0%
CyA+MMF Patients 208 169 130 120 127 112 94 116
Steroids Withdrawn 87 89 72 70 84 87 69 79
Rate 41.8% 52.7% 55.4% 58.3% 66.1% 77.7% 73.4% 68.1%
Tac+MMF Patients 944 1,089 1,210 1,418 1,608 1,449 1,597 1,709
Steroids Withdrawn 587 704 815 970 1,116 1,049 1,200 1,270
Rate 62.2% 64.6% 67.4% 68.4% 69.4% 72.4% 75.1% 74.3%
CyA+Aza Patients 95 46 37 1 22 11 4 2
Steroids Withdrawn 47 30 19 0 14 10 3 2
Rate 49.5% 65.2% 51.4% 0.0% 63.6% 90.9% 75.0% 100.0%
Tac+Aza Patients 60 58 72 75 24 2 1 5
Steroids Withdrawn 25 32 46 45 17 0 0 2
Rate 41.7% 55.2% 63.9% 60.0% 70.8% 0.0% 0.0% 40.0%
CyA+Siro Patients 10 7 20 16 18 16 3 3
Steroids Withdrawn 7 3 13 9 15 16 2 1
Rate 70.0% 42.9% 65.0% 56.3% 83.3% 100.0% 66.7% 33.3%
Tac+Siro Patients 129 118 85 39 48 34 40 13
Steroids Withdrawn 84 84 66 26 29 20 31 10
Rate 65.1% 71.2% 77.6% 66.7% 60.4% 58.8% 77.5% 76.9%
Siro+MMF Patients 23 38 32 30 28 26 13 8
Steroids Withdrawn 17 28 22 23 22 19 11 5
Rate 73.9% 73.7% 68.8% 76.7% 78.6% 73.1% 84.6% 62.5%
Other Regimen Patients 197 169 135 143 184 106 97 81
Steroids Withdrawn 115 99 72 81 122 83 68 54
Rate 58.4% 58.6% 53.3% 56.6% 66.3% 78.3% 70.1% 66.7%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use two years after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.