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Table 15.5b

Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 265 369 252 195 202 200 171 151 155
Steroids Withdrawn 83 164 121 91 98 101 82 89 107
Rate 31.3% 44.4% 48.0% 46.7% 48.5% 50.5% 48.0% 58.9% 69.0%
CyA Patients 17 7 5 6 - 1 1 - 0
Steroids Withdrawn 3 4 3 2 - 1 1 - -
Rate 17.6% 57.1% 60.0% 33.3% - 100.0% 100.0% - -
Tac Patients 101 131 93 68 65 60 67 57 46
Steroids Withdrawn 34 58 43 28 36 27 29 32 31
Rate 33.7% 44.3% 46.2% 41.2% 55.4% 45.0% 43.3% 56.1% 67.4%
CyA+MMF Patients 17 22 16 13 11 7 2 4 4
Steroids Withdrawn 4 11 10 11 7 5 2 2 3
Rate 23.5% 50.0% 62.5% 84.6% 63.6% 71.4% 100.0% 50.0% 75.0%
Tac+MMF Patients 94 153 105 98 108 118 96 77 98
Steroids Withdrawn 25 65 55 48 49 61 50 51 69
Rate 26.6% 42.5% 52.4% 49.0% 45.4% 51.7% 52.1% 66.2% 70.4%
CyA+Aza Patients 3 1 4 2 2 2 - 3 1
Steroids Withdrawn 1 0 0 1 0 1 - 0 1
Rate 33.3% 0.0% 0.0% 50.0% 0.0% 50.0% - 0.0% 100.0%
Tac+Aza Patients 2 - 2 - - 0 - 1 1
Steroids Withdrawn 1 - 1 - - - - 0 1
Rate 50.0% - 50.0% - - - - 0.0% 100.0%
CyA+Siro Patients 3 3 2 - 1 - - - -
Steroids Withdrawn 3 2 1 - 1 - - - -
Rate 100.0% 66.7% 50.0% - 100.0% - - - -
Tac+Siro Patients 12 23 9 1 2 1 1 3 -
Steroids Withdrawn 5 10 4 0 2 1 0 1 -
Rate 41.7% 43.5% 44.4% 0.0% 100.0% 100.0% 0.0% 33.3% -
Siro+MMF Patients 1 4 2 1 1 1 - 2 -
Steroids Withdrawn 0 2 2 0 1 1 - 2 -
Rate 0.0% 50.0% 100.0% 0.0% 100.0% 100.0% - 100.0% -
Other Regimen Patients 15 25 14 6 12 10 4 4 5
Steroids Withdrawn 7 12 2 1 2 4 0 1 2
Rate 46.7% 48.0% 14.3% 16.7% 16.7% 40.0% 0.0% 25.0% 40.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use one year after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.