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Table 15.5b

Steroid Withdrawal Rate at Two Years Following Transplantation, 2000 to 2007

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007
Total Patients 250 345 236 191 183 164 139 126
Steroids Withdrawn 135 223 147 121 121 112 96 92
Rate 54.0% 64.6% 62.3% 63.4% 66.1% 68.3% 69.1% 73.0%
CyA Patients 16 5 5 6 - 1 1 -
Steroids Withdrawn 11 3 5 4 - 1 1 -
Rate 68.8% 60.0% 100.0% 66.7% - 100.0% 100.0% -
Tac Patients 93 121 89 64 61 56 59 45
Steroids Withdrawn 49 75 59 33 42 38 36 28
Rate 52.7% 62.0% 66.3% 51.6% 68.9% 67.9% 61.0% 62.2%
CyA+MMF Patients 14 22 13 13 9 7 2 3
Steroids Withdrawn 4 17 10 12 8 6 2 3
Rate 28.6% 77.3% 76.9% 92.3% 88.9% 85.7% 100.0% 100.0%
Tac+MMF Patients 93 144 98 99 95 86 73 67
Steroids Withdrawn 54 99 57 67 60 57 55 56
Rate 58.1% 68.8% 58.2% 67.7% 63.2% 66.3% 75.3% 83.6%
CyA+Aza Patients 3 1 4 2 2 2 - 3
Steroids Withdrawn 1 0 2 1 2 2 - 2
Rate 33.3% 0.0% 50.0% 50.0% 100.0% 100.0% - 66.7%
Tac+Aza Patients 2 - 2 - - 0 - 1
Steroids Withdrawn 1 - 2 - - - - 0
Rate 50.0% - 100.0% - - - - 0.0%
CyA+Siro Patients 2 3 2 - 1 - - -
Steroids Withdrawn 1 3 1 - 1 - - -
Rate 50.0% 100.0% 50.0% - 100.0% - - -
Tac+Siro Patients 10 22 9 1 2 1 1 3
Steroids Withdrawn 7 13 5 1 2 1 0 1
Rate 70.0% 59.1% 55.6% 100.0% 100.0% 100.0% 0.0% 33.3%
Siro+MMF Patients 1 3 2 - 1 1 - 1
Steroids Withdrawn 0 0 2 - 1 1 - 1
Rate 0.0% 0.0% 100.0% - 100.0% 100.0% - 100.0%
Other Regimen Patients 16 24 12 6 12 10 3 3
Steroids Withdrawn 7 13 4 3 5 6 2 1
Rate 43.8% 54.2% 33.3% 50.0% 41.7% 60.0% 66.7% 33.3%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use two years after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.