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Table 15.6

Steroid Withdrawal Rate at One Year Following Transplantation, 2000 to 2008

Recipients of Heart Transplants

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 1,596 1,691 1,679 1,519 1,539 1,586 1,622 1,607 1,510
Steroids Withdrawn 279 359 391 390 360 440 447 468 547
Rate 17.5% 21.2% 23.3% 25.7% 23.4% 27.7% 27.6% 29.1% 36.2%
CyA Patients 67 27 43 25 11 10 23 18 11
Steroids Withdrawn 7 5 13 4 3 3 2 3 1
Rate 10.4% 18.5% 30.2% 16.0% 27.3% 30.0% 8.7% 16.7% 9.1%
Tac Patients 34 59 64 42 32 34 27 39 35
Steroids Withdrawn 12 14 20 11 10 16 14 9 18
Rate 35.3% 23.7% 31.3% 26.2% 31.3% 47.1% 51.9% 23.1% 51.4%
CyA+MMF Patients 936 926 743 701 667 550 522 443 327
Steroids Withdrawn 161 177 161 159 158 133 137 113 92
Rate 17.2% 19.1% 21.7% 22.7% 23.7% 24.2% 26.2% 25.5% 28.1%
Tac+MMF Patients 134 320 393 445 598 769 851 958 1,006
Steroids Withdrawn 25 80 75 121 144 242 243 313 394
Rate 18.7% 25.0% 19.1% 27.2% 24.1% 31.5% 28.6% 32.7% 39.2%
CyA+Aza Patients 246 171 115 76 65 38 36 25 10
Steroids Withdrawn 40 40 30 22 12 5 11 3 4
Rate 16.3% 23.4% 26.1% 28.9% 18.5% 13.2% 30.6% 12.0% 40.0%
Tac+Aza Patients 35 21 21 19 17 16 21 12 19
Steroids Withdrawn 7 2 4 6 2 7 7 5 8
Rate 20.0% 9.5% 19.0% 31.6% 11.8% 43.8% 33.3% 41.7% 42.1%
CyA+Siro Patients 10 3 17 34 2 1 2 - 2
Steroids Withdrawn 2 1 11 17 0 0 0 - 2
Rate 20.0% 33.3% 64.7% 50.0% 0.0% 0.0% 0.0% - 100.0%
Tac+Siro Patients 2 36 101 30 12 14 11 0 0
Steroids Withdrawn 0 2 23 11 3 5 8 - -
Rate 0.0% 5.6% 22.8% 36.7% 25.0% 35.7% 72.7% - -
Siro+MMF Patients - 3 5 16 14 14 18 3 3
Steroids Withdrawn - 1 0 3 1 1 3 0 1
Rate - 33.3% 0.0% 18.8% 7.1% 7.1% 16.7% 0.0% 33.3%
Other Regimen Patients 132 125 177 131 121 140 111 109 97
Steroids Withdrawn 25 37 54 36 27 28 22 22 27
Rate 18.9% 29.6% 30.5% 27.5% 22.3% 20.0% 19.8% 20.2% 27.8%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use one year after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.