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Table 15.6

Steroid Withdrawal Rate at Two Years Following Transplantation, 2000 to 2007

Recipients of Heart Transplants

Discharge Regimen Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007
Total Patients 1,558 1,581 1,561 1,460 1,433 1,362 1,333 1,332
Steroids Withdrawn 471 558 546 556 580 583 606 640
Rate 30.2% 35.3% 35.0% 38.1% 40.5% 42.8% 45.5% 48.0%
CyA Patients 66 28 39 22 10 9 20 15
Steroids Withdrawn 21 9 21 9 5 3 3 5
Rate 31.8% 32.1% 53.8% 40.9% 50.0% 33.3% 15.0% 33.3%
Tac Patients 31 56 58 39 30 28 22 29
Steroids Withdrawn 17 21 26 11 21 15 16 14
Rate 54.8% 37.5% 44.8% 28.2% 70.0% 53.6% 72.7% 48.3%
CyA+MMF Patients 903 863 699 677 615 476 436 396
Steroids Withdrawn 245 268 237 243 240 187 178 175
Rate 27.1% 31.1% 33.9% 35.9% 39.0% 39.3% 40.8% 44.2%
Tac+MMF Patients 130 300 364 426 561 642 688 755
Steroids Withdrawn 39 139 127 172 232 316 333 382
Rate 30.0% 46.3% 34.9% 40.4% 41.4% 49.2% 48.4% 50.6%
CyA+Aza Patients 244 162 101 73 61 33 30 24
Steroids Withdrawn 95 59 28 28 16 8 17 9
Rate 38.9% 36.4% 27.7% 38.4% 26.2% 24.2% 56.7% 37.5%
Tac+Aza Patients 32 21 20 19 16 14 18 11
Steroids Withdrawn 7 5 3 6 5 8 6 5
Rate 21.9% 23.8% 15.0% 31.6% 31.3% 57.1% 33.3% 45.5%
CyA+Siro Patients 10 3 17 33 2 1 1 -
Steroids Withdrawn 6 1 13 24 1 0 0 -
Rate 60.0% 33.3% 76.5% 72.7% 50.0% 0.0% 0.0% -
Tac+Siro Patients 15 30 97 30 12 14 11 0
Steroids Withdrawn 0 3 34 12 10 7 8 -
Rate 0.0% 10.0% 35.1% 40.0% 83.3% 50.0% 72.7% -
Siro+MMF Patients - 3 5 16 14 13 15 3
Steroids Withdrawn - 1 0 4 1 3 6 1
Rate - 33.3% 0.0% 25.0% 7.1% 23.1% 40.0% 33.3%
Other Regimen Patients 127 115 161 125 112 132 92 99
Steroids Withdrawn 41 52 57 47 49 36 39 49
Rate 32.3% 45.2% 35.4% 37.6% 43.8% 27.3% 42.4% 49.5%


Source: OPTN/SRTR Data as of October 1, 2010.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning

graft and maintenance drug use two years after transplantation.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;

Siro: Sirolimus.