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Pancreas
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Deceased Organ Donation
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Table 15.7
Immunosuppression Use for Maintenance by Regimen
Two Years Following Transplantation, 1999 to 2007
Recipients with Kidney Transplants
Transplant Year
1999
2000
2001
2002
2003
2004
2005
2006
2007
Transplants
12,765
13,620
14,276
14,779
15,137
16,006
16,483
17,095
16,634
Functioning Graft at 2 Years PostTx
10,225
11,064
11,837
12,311
12,633
13,388
13,767
14,550
14,340
With Maintenance Use Recorded at 2 Years PostTx
9,705
10,831
11,529
11,993
12,344
13,041
11,104
10,795
10,371
CyA
0.7%
0.2%
0.2%
0.1%
0.1%
0.1%
0.1%
0.2%
0.1%
Tac
0.8%
0.8%
1.5%
1.8%
1.9%
2.3%
3.1%
3.1%
2.6%
--- + MMF/MPA
0.1%
0.1%
0.1%
0.1%
0.3%
0.3%
0.3%
0.2%
0.2%
CyA + MMF/MPA
1.1%
1.4%
1.5%
1.7%
2.3%
2.3%
2.1%
1.6%
1.5%
Tac + MMF/MPA
2.2%
2.9%
4.4%
6.5%
9.9%
15.5%
22.1%
26.0%
27.5%
--- + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet
0.2%
0.1%
0.1%
0.1%
0.0%
0.1%
0.1%
0.0%
0.0%
Tac + OtherAntimet
0.2%
0.2%
0.2%
0.3%
0.2%
0.3%
0.4%
0.6%
0.7%
--- + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
--- + Siro/Evero
0.0%
0.2%
0.3%
0.2%
0.1%
0.2%
0.2%
0.2%
0.1%
CyA + Siro/Evero
0.2%
0.3%
0.4%
0.8%
0.8%
0.8%
1.0%
0.8%
0.8%
Tac + Siro/Evero
0.1%
0.9%
2.1%
2.4%
2.7%
2.1%
1.6%
1.0%
0.7%
--- + MMF/MPA + Siro/Evero
0.0%
0.2%
0.5%
0.7%
1.4%
1.9%
2.4%
2.5%
2.0%
CyA + MMF/MPA + Siro/Evero
0.0%
0.1%
0.1%
0.0%
0.1%
0.0%
0.0%
0.0%
0.0%
Tac + MMF/MPA + Siro/Evero
0.1%
0.2%
0.3%
0.5%
0.8%
0.7%
0.8%
0.6%
0.7%
--- + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
--- + Steroids
0.7%
0.3%
0.5%
0.4%
0.5%
0.2%
0.2%
0.2%
0.2%
CyA + Steroids
6.9%
4.1%
2.4%
1.5%
1.4%
0.9%
0.7%
0.5%
0.6%
Tac + Steroids
7.2%
7.4%
6.5%
6.1%
5.1%
4.5%
4.4%
4.7%
5.2%
--- + MMF/MPA + Steroids
2.0%
1.4%
1.3%
1.3%
1.1%
1.2%
1.1%
0.9%
0.7%
CyA + MMF/MPA + Steroids
36.3%
31.0%
22.8%
18.5%
14.0%
12.1%
7.4%
5.1%
4.3%
Tac + MMF/MPA + Steroids
27.3%
29.7%
35.0%
38.6%
41.3%
40.0%
40.4%
41.0%
43.2%
--- + OtherAntimet + Steroids
0.1%
0.1%
0.1%
0.1%
0.1%
0.1%
0.1%
0.1%
0.1%
CyA + OtherAntimet + Steroids
4.6%
2.9%
1.5%
0.7%
0.5%
0.3%
0.2%
0.1%
0.2%
Tac + OtherAntimet + Steroids
2.1%
2.0%
2.0%
1.6%
1.4%
1.3%
1.3%
1.6%
1.6%
--- + Siro/Evero + Steroids
0.5%
0.7%
1.0%
0.7%
0.9%
0.9%
0.8%
0.5%
0.5%
CyA + Siro/Evero + Steroids
2.3%
3.7%
2.9%
2.5%
1.9%
1.4%
1.1%
1.0%
1.1%
Tac + Siro/Evero + Steroids
1.3%
4.8%
6.5%
5.6%
4.4%
3.2%
2.3%
1.8%
0.9%
Other Regimen
3.0%
4.2%
5.8%
6.9%
6.7%
7.1%
5.7%
5.3%
4.2%
Source: OPTN/SRTR Data as of October 1, 2010.
Percentages are calculated based on the total number of patients with maintenance use at two years following transplantation. They sum to 100 percent for each column
---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.
MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.
"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.