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Table 15.14
Immunosuppression Use for Maintenance by Regimen
Two Years Following Transplantation, 1999 to 2007
Recipients with Lung Transplants
Transplant Year
1999
2000
2001
2002
2003
2004
2005
2006
2007
Transplants
922
977
1,083
1,054
1,099
1,185
1,407
1,406
1,471
Functioning Graft at 2 Years PostTx
583
658
719
752
791
872
994
1,023
1,004
With Maintenance Use Recorded at 2 Years PostTx
551
614
680
735
780
861
850
860
860
CyA
0.2%
0.0%
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac
0.2%
0.0%
0.3%
0.1%
0.4%
0.2%
0.1%
0.1%
0.2%
--- + MMF/MPA
0.0%
0.2%
0.1%
0.1%
0.0%
0.1%
0.0%
0.0%
0.5%
CyA + MMF/MPA
0.2%
0.0%
0.3%
0.0%
0.1%
0.0%
0.0%
0.0%
0.0%
Tac + MMF/MPA
0.2%
0.3%
0.7%
0.5%
0.5%
0.7%
1.1%
0.9%
0.5%
--- + OtherAntimet
0.4%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet
0.2%
0.2%
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + OtherAntimet
0.5%
0.2%
0.6%
1.0%
0.5%
0.1%
0.1%
0.0%
0.0%
--- + Siro/Evero
0.0%
0.0%
0.3%
0.0%
0.1%
0.0%
0.1%
0.0%
0.0%
CyA + Siro/Evero
0.2%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + Siro/Evero
0.2%
0.2%
0.3%
0.1%
0.5%
0.1%
0.2%
0.2%
0.1%
--- + MMF/MPA + Siro/Evero
0.0%
0.0%
0.0%
0.1%
0.1%
0.0%
0.1%
0.0%
0.1%
Tac + MMF/MPA + Siro/Evero
0.0%
0.3%
0.1%
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
--- + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
Tac + OtherAntimet + Siro/Evero
0.0%
0.0%
0.1%
0.1%
0.0%
0.0%
0.0%
0.1%
0.0%
--- + Steroids
0.7%
0.3%
0.6%
0.0%
0.6%
0.3%
0.2%
0.0%
0.3%
CyA + Steroids
4.9%
2.6%
1.2%
1.9%
1.7%
0.5%
2.0%
1.6%
2.1%
Tac + Steroids
5.1%
7.5%
8.1%
9.1%
9.6%
11.1%
10.9%
9.5%
12.8%
--- + MMF/MPA + Steroids
0.4%
0.5%
0.4%
0.5%
0.1%
0.2%
0.2%
0.1%
0.0%
CyA + MMF/MPA + Steroids
14.3%
14.7%
12.1%
8.8%
8.3%
5.5%
4.6%
4.5%
5.5%
Tac + MMF/MPA + Steroids
23.4%
27.9%
32.8%
35.1%
33.7%
41.8%
42.6%
47.1%
47.4%
--- + OtherAntimet + Steroids
0.2%
0.2%
0.3%
0.3%
0.1%
0.1%
0.1%
0.0%
0.1%
CyA + OtherAntimet + Steroids
22.1%
16.6%
7.5%
6.3%
7.6%
5.3%
4.5%
4.3%
2.0%
Tac + OtherAntimet + Steroids
16.3%
17.1%
17.4%
20.8%
20.6%
20.9%
18.6%
20.1%
15.9%
--- + Siro/Evero + Steroids
0.2%
0.2%
0.1%
0.4%
0.3%
0.5%
0.9%
0.3%
0.3%
CyA + Siro/Evero + Steroids
0.9%
1.3%
1.3%
0.7%
0.9%
0.3%
0.1%
0.2%
0.6%
Tac + Siro/Evero + Steroids
4.9%
4.4%
5.4%
6.3%
5.9%
4.9%
5.8%
4.2%
3.8%
Other Regimen
4.4%
5.5%
9.6%
7.2%
7.9%
7.2%
7.6%
6.5%
7.7%
Source: OPTN/SRTR Data as of October 1, 2010.
Percentages are calculated based on the total number of patients with maintenance use at two years following transplantation. They sum to 100 percent for each column
---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.
MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.
"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.