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Table 5.6f
Immunosuppression Use for Maintenance by Regimen
One Year Following Transplantation, 1999 to 2008
Recipients with Kidney Transplants
Transplant Year
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
Transplants
12,765
13,620
14,276
14,779
15,137
16,006
16,483
17,095
16,634
16,521
Functioning Graft at 1 Year PostTx
11,041
11,823
12,728
13,251
13,584
14,437
14,808
15,484
15,195
15,216
With Maintenance Use Recorded at 1 Year PostTx
10,465
11,208
12,498
12,937
13,236
14,097
14,568
15,143
14,706
14,692
CyA
0.7%
0.6%
0.1%
0.1%
0.1%
0.1%
0.1%
0.2%
0.1%
0.1%
Tac
0.5%
0.5%
1.1%
1.8%
2.1%
2.2%
2.6%
2.6%
2.2%
2.4%
--- + MMF/MPA
0.1%
0.0%
0.1%
0.1%
0.1%
0.2%
0.2%
0.3%
0.2%
0.2%
CyA + MMF/MPA
0.5%
1.0%
1.1%
1.5%
1.9%
2.1%
1.9%
1.8%
1.7%
1.2%
Tac + MMF/MPA
1.7%
1.8%
2.8%
5.7%
8.2%
14.1%
20.6%
24.2%
27.1%
26.3%
--- + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet
0.2%
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + OtherAntimet
0.1%
0.2%
0.1%
0.1%
0.1%
0.2%
0.2%
0.4%
0.4%
0.5%
--- + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + MMF/MPA + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.1%
0.1%
--- + Siro/Evero
0.1%
0.2%
0.2%
0.1%
0.1%
0.2%
0.2%
0.1%
0.1%
0.1%
CyA + Siro/Evero
0.2%
0.3%
0.2%
0.7%
1.0%
0.9%
0.7%
0.8%
0.7%
0.6%
Tac + Siro/Evero
0.1%
0.7%
1.6%
2.2%
2.4%
2.1%
1.7%
1.3%
1.1%
0.7%
--- + MMF/MPA + Siro/Evero
0.0%
0.1%
0.3%
0.5%
1.1%
1.3%
1.6%
2.0%
1.2%
1.0%
CyA + MMF/MPA + Siro/Evero
0.0%
0.2%
0.0%
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + MMF/MPA + Siro/Evero
0.0%
0.3%
0.3%
0.4%
0.8%
0.7%
0.6%
0.5%
0.6%
0.6%
--- + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
--- + Steroids
0.5%
0.6%
0.7%
0.5%
0.4%
0.3%
0.2%
0.3%
0.2%
0.3%
CyA + Steroids
6.5%
4.3%
2.5%
1.6%
1.5%
1.1%
0.5%
0.4%
0.4%
0.4%
Tac + Steroids
5.9%
6.3%
5.9%
5.7%
4.9%
3.9%
3.6%
4.3%
4.1%
4.8%
--- + MMF/MPA + Steroids
1.5%
0.9%
0.9%
0.9%
0.8%
0.8%
0.9%
1.2%
0.9%
0.9%
CyA + MMF/MPA + Steroids
39.2%
31.7%
24.2%
19.9%
15.5%
12.5%
8.8%
6.5%
5.3%
4.1%
Tac + MMF/MPA + Steroids
28.3%
31.5%
37.5%
39.8%
42.6%
42.9%
43.9%
44.1%
46.0%
48.5%
--- + OtherAntimet + Steroids
0.2%
0.1%
0.1%
0.1%
0.1%
0.0%
0.1%
0.1%
0.1%
0.1%
CyA + OtherAntimet + Steroids
5.4%
3.0%
1.7%
0.9%
0.5%
0.4%
0.3%
0.2%
0.2%
0.1%
Tac + OtherAntimet + Steroids
2.2%
1.9%
2.0%
1.5%
1.3%
1.0%
0.9%
1.1%
1.2%
1.7%
--- + Siro/Evero + Steroids
0.3%
0.5%
0.7%
0.7%
0.6%
0.7%
0.6%
0.4%
0.4%
0.4%
CyA + Siro/Evero + Steroids
2.1%
4.0%
3.3%
2.7%
2.0%
1.6%
1.3%
1.0%
0.9%
0.8%
Tac + Siro/Evero + Steroids
0.9%
4.7%
7.1%
5.9%
5.1%
3.6%
2.4%
1.7%
1.0%
0.6%
Other Regimen
2.8%
4.4%
5.5%
6.5%
6.5%
7.2%
6.0%
4.5%
3.8%
3.4%
Source: OPTN/SRTR Data as of October 1, 2010.
Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.
---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.
MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.
"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.