Flash e-reader

 Go to e-reader chapter








PDF FormatRequires Adobe Acrobat Reader

Table 5.6h

Persistency of Discharge Regimen by Follow-up Period, 2004 to 2008

Recipients with Kidney Transplants

  Year of Transplant
2004 2005 2006 2007 2008
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) 35 19 17 22 13
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 84.8% 68.4% 94.1% 86.4% 92.3%
1 Year PostTx (%) 75.4% 57.0% 69.0% 72.7% 83.1%
2 Years PostTx (%) 69.1% 50.7% 62.7% 61.5% 71.2%
3 Years PostTx (%) 62.9% 50.7% 62.7% 61.5% -
CyA+MMF At Discharge (N) 2,438 1,770 1,428 1,214 850
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 85.3% 89.1% 89.6% 90.3% 88.8%
1 Year PostTx (%) 76.3% 80.8% 81.5% 80.5% 77.9%
2 Years PostTx (%) 68.6% 73.7% 74.4% 72.4% 69.5%
3 Years PostTx (%) 62.9% 66.9% 68.4% 65.7% -
CyA+Siro At Discharge (N) 398 367 294 232 254
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 82.9% 80.0% 77.9% 80.4% 81.8%
1 Year PostTx (%) 74.2% 71.1% 66.2% 72.4% 73.7%
2 Years PostTx (%) 64.3% 64.1% 55.7% 62.9% 64.3%
3 Years PostTx (%) 52.0% 53.1% 48.4% 53.3% -
Siro+MMF At Discharge (N) 406 368 277 158 147
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 74.9% 79.2% 85.2% 79.6% 87.0%
1 Year PostTx (%) 62.6% 68.5% 74.8% 69.0% 80.9%
2 Years PostTx (%) 55.6% 62.5% 67.1% 61.4% 80.9%
3 Years PostTx (%) 50.8% 55.8% 60.1% 53.9% -
Tac+Aza At Discharge (N) 79 46 62 50 51
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 65.8% 71.7% 80.0% 76.0% 88.2%
1 Year PostTx (%) 51.5% 56.5% 65.5% 55.9% 71.8%
2 Years PostTx (%) 44.6% 52.2% 60.0% 41.9% 63.8%
3 Years PostTx (%) 41.7% 50.0% 48.3% 37.7% -
Tac+MMF At Discharge (N) 9,289 11,112 12,153 12,776 13,275
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 88.0% 90.4% 92.2% 93.5% 93.7%
1 Year PostTx (%) 81.4% 84.6% 86.4% 88.0% 88.4%
2 Years PostTx (%) 74.7% 78.2% 80.6% 82.3% 82.0%
3 Years PostTx (%) 69.6% 73.6% 75.6% 76.9% -
Tac+Siro At Discharge (N) 794 537 640 230 115
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 74.4% 80.1% 84.2% 86.0% 86.1%
1 Year PostTx (%) 61.6% 69.9% 72.4% 77.9% 69.5%
2 Years PostTx (%) 56.3% 59.7% 67.6% 68.3% 63.0%
3 Years PostTx (%) 50.8% 53.9% 63.6% 61.7% -


Source: OPTN/SRTR Data as of October 1, 2010.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen

(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.&

Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.