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Table 6.6f
Immunosuppression Use for Maintenance by Regimen
One Year Following Transplantation, 1999 to 2008
Recipients with Pancreas Transplant Alone (PTA) Transplants
Transplant Year
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
Transplants
139
134
168
180
160
183
199
174
210
223
Functioning Graft at 1 Year PostTx
109
96
122
140
115
137
149
125
152
160
With Maintenance Use Recorded at 1 Year PostTx
108
93
120
139
115
137
149
125
151
159
CyA
0.0%
1.1%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Tac
1.9%
2.2%
10.8%
5.8%
17.4%
14.6%
18.8%
16.8%
7.3%
11.3%
--- + MMF/MPA
0.0%
0.0%
0.0%
1.4%
9.6%
3.6%
1.3%
0.0%
0.0%
0.0%
CyA + MMF/MPA
0.0%
0.0%
0.8%
1.4%
0.9%
0.7%
0.0%
0.8%
0.7%
0.0%
Tac + MMF/MPA
3.7%
2.2%
2.5%
7.9%
7.0%
11.7%
18.1%
16.0%
17.9%
25.2%
Tac + OtherAntimet
0.0%
0.0%
0.0%
0.0%
0.9%
0.7%
1.3%
0.0%
1.3%
0.0%
--- + Siro/Evero
0.0%
0.0%
1.7%
0.7%
0.9%
2.2%
0.0%
0.0%
0.0%
0.0%
CyA + Siro/Evero
0.0%
0.0%
0.0%
0.7%
1.7%
0.0%
0.7%
0.8%
0.0%
0.0%
Tac + Siro/Evero
0.9%
2.2%
0.8%
9.4%
7.0%
8.0%
8.7%
6.4%
5.3%
3.1%
--- + MMF/MPA + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.9%
0.7%
1.3%
0.0%
0.7%
0.0%
CyA + MMF/MPA + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.7%
0.0%
Tac + MMF/MPA + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.9%
2.9%
3.4%
11.2%
10.6%
7.5%
Tac + OtherAntimet + Siro/Evero
0.0%
0.0%
0.0%
0.0%
0.0%
0.7%
0.0%
0.8%
0.0%
0.0%
--- + Steroids
0.0%
0.0%
0.8%
0.7%
0.0%
0.7%
0.0%
0.0%
0.7%
0.0%
CyA + Steroids
0.0%
0.0%
0.0%
0.7%
0.9%
0.0%
0.0%
0.0%
0.0%
0.6%
Tac + Steroids
4.6%
9.7%
15.0%
13.7%
10.4%
12.4%
9.4%
24.0%
27.8%
20.8%
--- + MMF/MPA + Steroids
1.9%
1.1%
0.0%
1.4%
0.0%
0.0%
0.7%
0.0%
0.0%
0.0%
CyA + MMF/MPA + Steroids
5.6%
3.2%
4.2%
2.9%
2.6%
1.5%
1.3%
0.0%
0.0%
0.0%
Tac + MMF/MPA + Steroids
67.6%
52.7%
55.0%
38.1%
27.0%
23.4%
28.2%
20.8%
21.9%
28.9%
--- + OtherAntimet + Steroids
0.0%
0.0%
0.0%
0.0%
0.0%
0.7%
0.0%
0.0%
0.0%
0.0%
CyA + OtherAntimet + Steroids
0.9%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.7%
0.0%
Tac + OtherAntimet + Steroids
0.9%
4.3%
0.8%
0.0%
0.0%
2.2%
1.3%
0.0%
0.0%
0.0%
--- + Siro/Evero + Steroids
0.0%
2.2%
0.0%
1.4%
0.0%
1.5%
0.0%
0.0%
0.0%
0.0%
CyA + Siro/Evero + Steroids
0.9%
0.0%
0.0%
0.7%
0.9%
0.7%
0.0%
0.8%
0.7%
0.0%
Tac + Siro/Evero + Steroids
8.3%
12.9%
6.7%
10.8%
5.2%
2.9%
4.7%
0.0%
2.0%
1.9%
Other Regimen
2.8%
6.5%
0.8%
2.2%
6.1%
8.0%
0.7%
1.6%
2.0%
0.6%
Source: OPTN/SRTR Data as of October 1, 2010.
Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.
---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.
MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.
"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.