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Table 6.6h

Persistency of Discharge Regimen by Follow-up Period, 2004 to 2008

Recipients with Pancreas Transplant Alone (PTA) Transplants

  Year of Transplant
2004 2005 2006 2007 2008
Discharge Regimen (w/ or w/o Steroid Use) CyA+MMF At Discharge (N) 1 - 2 3 -
At Discharge (%) 100.0% - 100.0% 100.0% -
6 Months PostTx (%) 100.0% - 0.0% 100.0% -
1 Year PostTx (%) 100.0% - 0.0% 66.7% -
2 Years PostTx (%) 100.0% - 0.0% 33.3% -
3 Years PostTx (%) 100.0% - 0.0% - -
CyA+Siro At Discharge (N) 1 - 1 - -
At Discharge (%) 100.0% - 100.0% - -
6 Months PostTx (%) - - 100.0% - -
1 Year PostTx (%) - - 100.0% - -
2 Years PostTx (%) - - 100.0% - -
3 Years PostTx (%) - - - - -
Siro+MMF At Discharge (N) - 2 - - -
At Discharge (%) - 100.0% - - -
6 Months PostTx (%) - 100.0% - - -
1 Year PostTx (%) - 100.0% - - -
2 Years PostTx (%) - 0.0% - - -
3 Years PostTx (%) - 0.0% - - -
Tac+Aza At Discharge (N) 2 - - 2 -
At Discharge (%) 100.0% - - 100.0% -
6 Months PostTx (%) 100.0% - - 100.0% -
1 Year PostTx (%) 100.0% - - 100.0% -
2 Years PostTx (%) 50.0% - - 100.0% -
3 Years PostTx (%) 50.0% - - 100.0% -
Tac+MMF At Discharge (N) 62 91 61 79 107
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 78.7% 89.9% 86.9% 88.5% 90.6%
1 Year PostTx (%) 70.5% 84.3% 73.8% 75.2% 78.8%
2 Years PostTx (%) 62.1% 72.8% 62.2% 66.7% 60.1%
3 Years PostTx (%) 49.9% 68.1% 58.5% 66.7% -
Tac+Siro At Discharge (N) 13 18 17 9 7
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 84.6% 77.8% 76.5% 44.4% 57.1%
1 Year PostTx (%) 61.5% 72.2% 35.3% 44.4% 42.9%
2 Years PostTx (%) 46.2% 55.6% 17.6% 0.0% 21.4%
3 Years PostTx (%) 46.2% 44.4% 11.8% 0.0% -


Source: OPTN/SRTR Data as of October 1, 2010.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen

(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.&

Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.