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Table 7.6d

Immunosuppression Use for Maintenance by Regimen

Prior to Discharge, 2000 to 2009

Recipients with Pancreas After Kidney (PAK) Transplants

  Transplant Year
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Functioning Graft at Discharge 278 287 336 315 380 306 255 240 192 183
With Immunosuppression Info 277 286 335 312 375 303 249 230 191 178
CyA 0.0% 0.3% 0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac 4.0% 3.8% 4.8% 1.3% 2.7% 3.0% 2.4% 2.6% 1.0% 1.7%
--- + MMF/MPA 0.0% 0.0% 0.0% 5.8% 5.1% 2.0% 0.0% 0.4% 0.5% 1.1%
CyA + MMF/MPA 0.0% 0.7% 0.3% 1.0% 1.3% 2.0% 0.8% 0.9% 0.0% 1.7%
Tac + MMF/MPA 0.0% 0.3% 0.9% 6.4% 8.0% 17.8% 23.3% 30.0% 31.9% 29.2%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.5% 0.0%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.5% 0.3% 0.0% 0.0% 0.5% 0.0%
CyA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 1.1% 1.0% 2.4% 0.4% 1.6% 0.0%
Tac + Siro/Evero 0.0% 1.0% 2.4% 2.2% 4.0% 4.3% 2.4% 0.0% 0.0% 0.0%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.3% 1.6% 0.3% 0.4% 0.4% 0.5% 0.0%
CyA + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.3% 1.6% 0.8% 1.7% 3.6% 7.0% 3.1% 6.2%
--- + Steroids 1.8% 0.3% 0.3% 1.0% 2.7% 3.3% 0.0% 0.0% 0.5% 0.0%
CyA + Steroids 0.0% 0.0% 0.3% 0.3% 0.5% 0.0% 0.4% 0.4% 0.0% 0.0%
Tac + Steroids 4.3% 1.0% 2.4% 1.3% 2.1% 0.3% 0.8% 1.7% 1.0% 1.1%
--- + MMF/MPA + Steroids 0.0% 0.3% 1.5% 1.6% 1.6% 0.3% 0.4% 1.3% 1.6% 1.1%
CyA + MMF/MPA + Steroids 10.8% 5.6% 7.2% 5.1% 3.5% 2.3% 2.0% 1.7% 1.6% 1.1%
Tac + MMF/MPA + Steroids 67.5% 62.6% 60.6% 59.9% 55.2% 53.8% 53.0% 50.9% 51.8% 53.9%
CyA + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.3% 0.0% 0.0% 0.0% 0.4% 0.0% 0.0%
Tac + OtherAntimet + Steroids 1.8% 0.7% 0.3% 0.3% 0.3% 0.7% 0.0% 0.4% 1.0% 0.6%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.3% 0.3% 0.3% 0.3% 0.4% 0.0% 0.0% 0.0%
CyA + Siro/Evero + Steroids 1.8% 1.4% 2.1% 1.3% 0.8% 0.7% 0.0% 0.0% 0.0% 0.6%
Tac + Siro/Evero + Steroids 5.4% 15.7% 11.3% 6.1% 4.5% 2.6% 6.0% 0.0% 1.0% 0.6%
Other Regimen 2.5% 5.9% 4.8% 3.8% 3.5% 2.6% 1.6% 1.3% 1.6% 1.1%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages in each column sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.