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Table 7.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 220 305 305 375 344 420 343 293 261 213
Tx with Follow-up Immunosuppression Info 167 220 245 271 257 321 255 220 205 166
Corticosteroids Any in Category 100.0% 98.6% 98.8% 94.5% 78.6% 73.8% 74.9% 70.9% 60.0% 64.5%
Steroids 100.0% 98.6% 98.8% 94.5% 78.6% 73.8% 74.9% 70.9% 60.0% 64.5%
Cyclosporine Any in Category 14.4% 16.4% 15.1% 15.1% 11.3% 8.1% 6.7% 6.8% 5.9% 7.8%
Sandimmmune 2.4% 3.2% 0.8% 1.1% 0.0% 0.3% 0.0% 0.5% 0.5% 0.6%
Neoral 12.0% 12.3% 12.7% 11.8% 9.3% 5.0% 6.3% 6.4% 5.4% 6.0%
Gengraf 0.0% 0.9% 0.8% 2.2% 1.6% 2.8% 0.4% 0.0% 0.0% 1.2%
Eon 0.0% 0.0% 0.8% 0.0% 0.4% 0.0% 0.0% 0.0% 0.0% 0.0%
Tacrolimus Any in Category 91.0% 91.8% 91.8% 87.5% 82.9% 87.2% 92.5% 91.8% 93.7% 92.2%
Tacrolimus 91.0% 91.8% 91.8% 87.5% 82.9% 87.2% 92.5% 91.8% 93.2% 91.6%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.5% 0.6%
Antimetabolites Any in Category 95.2% 84.5% 80.4% 80.4% 84.8% 82.6% 90.6% 87.3% 90.2% 89.2%
Mycophenolate Mofetil 86.2% 78.6% 78.0% 78.2% 80.9% 79.4% 84.3% 75.5% 75.6% 69.9%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 2.2% 4.3% 8.6% 12.2% 14.5%
Azathioprine 9.0% 5.9% 2.4% 2.2% 3.5% 0.3% 2.0% 1.8% 1.0% 4.2%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.4% 0.6% 0.0% 1.4% 1.5% 0.6%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 7.2% 24.5% 30.6% 31.7% 27.2% 25.5% 19.2% 17.3% 19.0% 16.3%
Sirolimus 7.2% 24.5% 30.6% 31.7% 27.2% 25.5% 19.2% 17.3% 19.0% 16.3%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.