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Table 8.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Kidney-Pancreas Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 941 915 891 906 871 881 903 924 864 837
Tx with Follow-up Immunosuppression Info 859 839 818 821 785 791 823 820 767 748
Corticosteroids Any in Category 99.5% 95.6% 93.4% 89.4% 81.9% 75.9% 73.5% 71.6% 71.6% 75.1%
Steroids 99.5% 95.6% 93.4% 89.4% 81.9% 75.9% 73.5% 71.6% 71.6% 75.1%
Cyclosporine Any in Category 31.1% 23.0% 17.0% 13.4% 11.8% 8.6% 7.3% 7.0% 7.8% 5.5%
Cyclosporin 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Sandimmmune 5.0% 3.1% 1.8% 1.3% 0.6% 0.5% 0.1% 0.1% 0.4% 0.9%
Neoral 25.8% 18.7% 12.3% 8.8% 9.2% 6.7% 5.5% 5.5% 6.9% 4.0%
Gengraf 0.2% 1.2% 2.7% 3.2% 2.0% 1.4% 1.7% 1.3% 0.5% 0.4%
Eon 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1%
Tacrolimus Any in Category 80.7% 84.3% 89.2% 89.9% 87.6% 87.7% 93.3% 92.9% 94.1% 94.0%
Tacrolimus 80.7% 84.3% 89.2% 89.9% 87.6% 87.7% 93.3% 92.3% 93.9% 93.9%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 0.3% 0.1%
Antimetabolites Any in Category 95.7% 87.5% 80.3% 82.2% 82.5% 86.6% 86.3% 87.9% 89.7% 90.8%
Mycophenolate Mofetil 87.4% 81.2% 77.4% 79.8% 80.3% 80.2% 75.0% 69.9% 69.6% 62.2%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 4.7% 10.2% 16.0% 18.3% 26.2%
Azathioprine 8.3% 6.3% 2.9% 2.4% 2.2% 1.6% 0.9% 1.2% 1.3% 1.5%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.2% 0.9% 0.5% 0.9%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 5.2% 21.0% 31.2% 27.8% 27.5% 24.0% 22.2% 19.1% 15.0% 12.3%
Sirolimus 4.8% 20.5% 31.1% 27.8% 27.5% 24.0% 22.2% 19.1% 15.0% 12.3%
Everolimus 0.5% 0.5% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.