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Table 9.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 2000 to 2009

Recipients with Liver Transplants

  Year of Transplant
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009
Functioning Graft at Discharge 4,324 4,573 4,778 5,121 5,623 5,865 6,127 6,000 5,880 5,920
With Immunosuppression Info 4,310 4,567 4,775 5,116 5,595 5,796 6,062 5,965 5,840 5,909
Corticosteroids Any in Category 91.9% 90.2% 90.4% 82.4% 80.6% 78.9% 78.4% 76.1% 80.2% 81.3%
Steroids 91.9% 90.2% 90.4% 82.4% 80.6% 78.9% 78.4% 76.1% 80.2% 81.3%
Cyclosporine Any in Category 18.5% 11.9% 10.2% 8.7% 8.1% 7.0% 6.7% 7.1% 7.0% 7.0%
Cyclosporin 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1% 0.0% 0.1%
Sandimmmune 3.1% 1.3% 1.1% 0.4% 0.5% 0.6% 0.8% 0.9% 1.1% 0.8%
Neoral 15.3% 9.7% 7.4% 7.4% 6.6% 5.6% 4.3% 5.0% 4.6% 4.9%
Gengraf 0.1% 0.6% 1.5% 0.8% 0.8% 0.6% 1.0% 0.8% 1.0% 0.9%
Eon 0.0% 0.4% 0.2% 0.1% 0.2% 0.1% 0.5% 0.3% 0.2% 0.2%
Tacrolimus Any in Category 76.6% 83.1% 86.8% 88.8% 88.7% 90.8% 91.4% 91.7% 91.2% 89.2%
Tacrolimus 76.6% 83.1% 86.8% 88.8% 88.7% 90.8% 91.3% 90.8% 90.6% 88.8%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.9% 0.5% 0.4%
Antimetabolites Any in Category 48.3% 50.8% 51.6% 57.3% 58.3% 61.4% 69.2% 72.8% 77.2% 75.5%
Mycophenolate Mofetil 43.2% 47.7% 48.1% 54.1% 55.7% 58.5% 65.1% 67.3% 71.5% 66.2%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.4% 2.1% 3.7% 4.9% 5.3% 8.1%
Azathioprine 5.0% 3.0% 3.5% 3.2% 2.1% 0.7% 0.4% 0.6% 0.4% 1.2%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 9.4% 9.9% 6.6% 4.4% 5.0% 4.0% 3.7% 2.5% 2.2% 2.4%
Sirolimus 9.4% 9.9% 6.6% 4.4% 5.0% 4.0% 3.7% 2.5% 2.2% 2.1%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2%


Source: OPTN/SRTR Data as of October 1, 2010.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may

be prescribed more than one drug within the same category.