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Table 9.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1999 to 2008

Recipients with Liver Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Transplants 4,755 5,001 5,195 5,332 5,673 6,171 6,444 6,651 6,494 6,319
Tx with Follow-up Immunosuppression Info 3,643 3,890 4,090 4,304 4,566 4,940 5,054 5,303 5,155 4,973
Corticosteroids Any in Category 89.3% 90.5% 89.5% 87.2% 78.5% 75.4% 75.3% 72.0% 68.2% 69.3%
Steroids 89.3% 90.5% 89.5% 87.2% 78.5% 75.4% 75.3% 72.0% 68.2% 69.3%
Cyclosporine Any in Category 30.4% 23.4% 18.4% 14.0% 11.8% 11.6% 10.4% 9.9% 10.0% 10.1%
Cyclosporin 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1% 0.3%
Sandimmmune 7.0% 5.4% 3.7% 2.0% 0.7% 0.9% 1.1% 1.2% 1.3% 1.1%
Neoral 23.3% 17.3% 13.3% 9.8% 8.9% 9.2% 7.8% 6.7% 7.1% 6.5%
Gengraf 0.1% 0.5% 1.3% 2.0% 1.8% 1.3% 1.3% 1.7% 1.2% 1.7%
Eon 0.0% 0.1% 0.2% 0.2% 0.3% 0.2% 0.1% 0.2% 0.2% 0.5%
Tacrolimus Any in Category 76.6% 84.1% 89.1% 90.5% 90.5% 89.7% 91.7% 91.0% 90.7% 89.6%
Tacrolimus 76.6% 84.1% 89.1% 90.5% 90.5% 89.7% 91.7% 90.8% 90.5% 89.3%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.3% 0.3%
Antimetabolites Any in Category 49.3% 52.2% 53.5% 53.7% 55.1% 59.0% 66.3% 69.8% 69.9% 72.9%
Mycophenolate Mofetil 40.8% 46.2% 48.8% 49.3% 52.4% 55.5% 62.2% 64.4% 63.0% 65.5%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 2.8% 4.4% 5.4% 6.2%
Azathioprine 8.3% 5.9% 4.6% 4.3% 2.7% 2.9% 1.2% 1.0% 1.4% 1.2%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.1% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 3.2% 15.1% 16.6% 13.8% 12.2% 14.1% 13.8% 11.9% 9.9% 9.0%
Sirolimus 3.1% 15.1% 16.6% 13.8% 12.2% 14.1% 13.8% 11.8% 9.9% 8.8%
Everolimus 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2%


Source: OPTN/SRTR Data as of October 1, 2010.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within

the same category.