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Table 9.6g
Immunosuppression Use for Maintenance Between Discharge
and One Year Following Transplantation, 1999 to 2008
Recipients with Liver Transplants
Year of Transplant
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
Transplants
4,755
5,001
5,195
5,332
5,673
6,171
6,444
6,651
6,494
6,319
Tx with Follow-up Immunosuppression Info
3,643
3,890
4,090
4,304
4,566
4,940
5,054
5,303
5,155
4,973
Corticosteroids
Any in Category
89.3%
90.5%
89.5%
87.2%
78.5%
75.4%
75.3%
72.0%
68.2%
69.3%
Steroids
89.3%
90.5%
89.5%
87.2%
78.5%
75.4%
75.3%
72.0%
68.2%
69.3%
Cyclosporine
Any in Category
30.4%
23.4%
18.4%
14.0%
11.8%
11.6%
10.4%
9.9%
10.0%
10.1%
Cyclosporin
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
0.1%
0.1%
0.1%
0.3%
Sandimmmune
7.0%
5.4%
3.7%
2.0%
0.7%
0.9%
1.1%
1.2%
1.3%
1.1%
Neoral
23.3%
17.3%
13.3%
9.8%
8.9%
9.2%
7.8%
6.7%
7.1%
6.5%
Gengraf
0.1%
0.5%
1.3%
2.0%
1.8%
1.3%
1.3%
1.7%
1.2%
1.7%
Eon
0.0%
0.1%
0.2%
0.2%
0.3%
0.2%
0.1%
0.2%
0.2%
0.5%
Tacrolimus
Any in Category
76.6%
84.1%
89.1%
90.5%
90.5%
89.7%
91.7%
91.0%
90.7%
89.6%
Tacrolimus
76.6%
84.1%
89.1%
90.5%
90.5%
89.7%
91.7%
90.8%
90.5%
89.3%
Everolimus
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.2%
0.3%
0.3%
Antimetabolites
Any in Category
49.3%
52.2%
53.5%
53.7%
55.1%
59.0%
66.3%
69.8%
69.9%
72.9%
Mycophenolate Mofetil
40.8%
46.2%
48.8%
49.3%
52.4%
55.5%
62.2%
64.4%
63.0%
65.5%
Mycophenolate Sodium
0.0%
0.0%
0.0%
0.0%
0.0%
0.6%
2.8%
4.4%
5.4%
6.2%
Azathioprine
8.3%
5.9%
4.6%
4.3%
2.7%
2.9%
1.2%
1.0%
1.4%
1.2%
Leflunomide
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Cytoxan
0.1%
0.1%
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
mTOR Inhibitors
Any in Category
3.2%
15.1%
16.6%
13.8%
12.2%
14.1%
13.8%
11.9%
9.9%
9.0%
Sirolimus
3.1%
15.1%
16.6%
13.8%
12.2%
14.1%
13.8%
11.8%
9.9%
8.8%
Everolimus
0.1%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.2%
Source: OPTN/SRTR Data as of October 1, 2010.
Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.
Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within
the same category.